CUSTOM CGH ARRAY PROFILING OF COPY NUMBER VARIATIONS (CNVS) ON CHROMOSOME 6P21.32 (HLA LOCUS) IN PATIENTS WITH VENOUS MALFORMATIONS ASSOCIATED WITH MULTIPLE SCLEROSIS

Abstract Background Multiple sclerosis (MS) is a complex disorder thought to result from an interaction between environmental and genetic predisposing factors which have not yet been characterised, although it is known to be associated with the HLA region on 6p21.32.Recently, a picture of chronic cerebrospinal venous insufficiency (CCSVI), conseque

In modern conditions, the housing construction sector is dynamically developing and transforming under the influence of the turbulent processes of our time: globalization, digitalization, platformization, greening, etc.The purpose of the article is to identify new innovative forms of investment in housing construction and their features in differen

While classical ruins are seen as tourist destinations, contemporary or industrial ruins are dismissed as disused sites.In this paper I argue for the preservation of urban (or contemporary) ruins.I focus on one specific case, that of the Miami Marine Stadium in Miami, Florida USA.Since the 1990s the stadium has been derelict, a canvas for graffiti

Abstract Background The retina is a multi-layered sensory tissue that lines the back of the eye and acts at the interface of input light and visual perception.Its main function is to capture photons and convert them into electrical impulses that travel along the optic nerve to the brain where they are turned into images.It consists of neurons, nour

This scientific study aims to introduce a new type of topological space, called "Grill v-space", with the aim of contributing to scientific knowledge in this field.New generalizations were developed for both the local function and the Kuratowski closure function Foot Rest Cover in order to generalize their concepts.Subsequently, these generalizatio